Mariners vs. Brewers Prediction, Odds, Picks - July 22

Data Skrive

Julio Rodriguez and the Seattle Mariners will try to defeat Jackson Chourio and the Milwaukee Brewers at T-Mobile Park on Tuesday at 9:40 p.m. ET. The Mariners are the favorite in this one, at -123, while the underdog Brewers have +103 odds to win. Seattle is favored on the run line (-1.5). The over/under is 7 runs for this game (with +103 odds to hit the over and -125 odds to go under).

Here is everything you need from a betting perspective on the Mariners-Brewers game, regarding the run line, moneyline and total, plus expert picks.

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Mariners vs. Brewers Game Information & Odds

When: Tuesday, July 22, 2025 at 9:40 p.m. ET
Where: T-Mobile Park in Seattle, Washington
How to watch on TV: MLB Network, ROOT Sports NW, and FDSWI

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Mariners -123 +103 7 +103 -125 -1.5 +177 -213

Mariners vs. Brewers Prediction

Score Prediction: Mariners 5, Brewers 4
Total Prediction: Over 7 runs
Win Probabilities: Mariners 51%, Brewers 49%

Mariners vs. Brewers Betting Insights

This season, the Mariners have won 35 out of the 63 games, or 55.6%, in which they’ve been favored.
This season Seattle has won 27 of its 49 games, or 55.1%, when favored by at least -123 on the moneyline.
The Mariners have a 55.2% chance to win this game based on the implied probability of the moneyline.
The Brewers have been victorious in 26, or 52%, of the 50 contests they have been chosen as underdogs in this season.
Milwaukee has a win-loss record of 19-20 when favored by +103 or worse by oddsmakers this year.
The moneyline set for this matchup implies the Brewers have a 49.3% chance of coming away with a victory in the contest.

Mariners Recent Betting Performance

The Mariners have a 3-2 record over the five games they were favored on the moneyline in their last 10 matchups.
In their last 10 matchups (all had set totals), the Mariners combined with their opponents to hit the over on the run total eight times.
The Mariners’ ATS record is 5-5-0 over their past 10 games.

Mariners Recent Stats

Stat Avg/Total Record 6-4 Runs Per Game 6.6 HR 20 ERA 4.99 K/9 9.5

Mariners Player Insights

Cal Raleigh is the Mariners best power option, hitting 38 round-trippers this season in addition to accumulating 83 RBI, both team highs.
Among all batters in MLB, Raleigh’s home run total places him first, and his RBI tally ranks him second.
Rodriguez has 17 doubles, three triples, 14 home runs and 30 walks while hitting .252.
Rodriguez ranks 62nd in homers and 55th in RBI on the year.
Rodriguez carries a two-game streak with at least one hit into this contest. In his last five games he is batting .400 with two doubles, two home runs, five walks and five RBIs.
Randy Arozarena has 22 doubles, a triple, 18 home runs and 45 walks while hitting .252.
J.P. Crawford’s .288 batting average leads his team.

Brewers Recent Betting Performance

In seven games as an underdog over the last 10 matchups, Milwaukee has a perfect record of 7-0.
The Brewers and their opponents have combined to hit the over six times in their last 10 games with a total.
Over their last 10 games, the Brewers are 9-1-0 against the spread.

Brewers Recent Stats

Stat Avg/Total Record 10-0 Runs Per Game 5.6 HR 11 ERA 2.47 K/9 10.2

Brewers Player Insights

Chourio has 25 doubles, three triples, 16 home runs and 18 walks while hitting .265.
In all of the majors, Chourio ranks 46th in homers and 18th in RBI.
Chourio carries a 14-game hitting streak into this matchup. During his last 10 games he is hitting .317 with a double, two home runs, a walk and 10 RBIs.
Christian Yelich has hit 19 home runs with 65 RBI, leading the team in both categories.
Yelich is currently 23rd in home runs and 13th in RBI in the major leagues.
Brice Turang is hitting .275 with 14 doubles, six home runs and 40 walks.
William Contreras has 17 doubles, six home runs and 56 walks while batting .243.