Cubs vs. Pirates Prediction, Odds, Picks - April 30

Data Skrive

Pete Crow-Armstrong and the Chicago Cubs will try to defeat Oneil Cruz and the Pittsburgh Pirates at PNC Park on Wednesday at 6:40 p.m. ET. The Pirates are +145 moneyline underdogs in this matchup against the favorite Cubs (-172). Chicago (-1.5) is the favorite on the run line. The over/under is 9 runs for this contest.

Here’s everything you need from a betting perspective on the Cubs-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Cubs vs. Pirates Game Information & Odds

When: Wednesday, April 30, 2025 at 6:40 p.m. ET
Where: PNC Park in Pittsburgh, Pennsylvania
How to watch on TV: SportsNet PT and MARQ

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Cubs -172 +145 9 +108 -128 -1.5 -110 -109

Cubs vs. Pirates Prediction

Score Prediction: Cubs 6, Pirates 5
Total Prediction: Over 9 runs
Win Probabilities: Cubs 54%, Pirates 46%

Cubs vs. Pirates Betting Insights

This season, the Cubs have been favored 14 times and won 10, or 71.4%, of those games.
Chicago has not entered a game this season with shorter moneyline odds than -172.
The bookmakers’ moneyline implies a 63.2% chance of a victory for the Cubs.
The Pirates have been underdogs in 18 games this season and have come away with the win six times (33.3%) in those contests.
This season, Pittsburgh has come away with a win two times in six chances when named as an underdog of at least +145 or worse on the moneyline.
The moneyline set for this matchup implies the Pirates have a 40.8% chance of walking away with the win.

Cubs Recent Betting Performance

The Cubs went 4-2 over the six games they were a moneyline favorite in their last 10 matchups.
Over their last 10 outings (all 10 of them had set totals), the Cubs and their opponents combined to hit the over five times.
The Cubs have put together a 4-6-0 record against the spread over their past 10 games.

Cubs Recent Stats

Stat Avg/Total Record 6-4 Runs Per Game 5.2 HR 12 ERA 4.02 K/9 8.3

Cubs Player Insights

Kyle Tucker has racked up a team-best batting average of .289, while leading the Cubs in home runs (seven) and runs batted in (25).
Of all batters in the majors, Tucker ranks 13th in homers and fifth in RBI.
Crow-Armstrong is hitting .286 with 10 doubles, a triple, five home runs and six walks.
Among all MLB hitters, Crow-Armstrong ranks 39th in homers and 22nd in RBI.
Carson Kelly is batting .341 with a double, a triple, six home runs and 15 walks.
Ian Happ has seven doubles, two home runs and 18 walks while hitting .260.

Pirates Recent Betting Performance

The Pirates have played as underdogs in seven of their past 10 games and won three of those contests.
The Pirates and their opponents have combined to hit the over five times in their last 10 games with a total.
The Pirates have a record of 5-5-0 ATS over their last 10 games.

Pirates Recent Stats

Stat Avg/Total Record 4-6 Runs Per Game 3.6 HR 11 ERA 3.89 K/9 7.8

Pirates Player Insights

Cruz has managed a team-high eight home runs and has driven in 16 runs.
Among all hitters in the big leagues, Cruz is eighth in home runs and 40th in RBI.
Andrew McCutchen has four doubles, three home runs and 11 walks while hitting .276.
McCutchen is 101st overall in homers and 144th in RBI this year.
Enmanuel Valdez is hitting .219 with three doubles, two triples, two home runs and 10 walks.
Ke’Bryan Hayes is hitting .235 with two doubles, a triple, a home run and eight walks.