Cardinals vs. Brewers Prediction, Odds, Picks - April 26

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Brice Turang and the Milwaukee Brewers hit the field on Saturday at Busch Stadium against Sonny Gray, who gets the start for the St. Louis Cardinals. First pitch will be at 2:15 p.m. ET. The favored Cardinals have -159 moneyline odds to win against the underdog Brewers, who are listed at +134. St. Louis is the run-line favorite (-1.5). The over/under for the game has been set at 7.5 runs.

Here is everything you need to know from a betting perspective on the Cardinals-Brewers game, regarding the run line, moneyline and total, plus expert picks.

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Cardinals vs. Brewers Game Information & Odds

When: Saturday, April 26, 2025 at 2:15 p.m. ET
Where: Busch Stadium in St. Louis, Missouri
How to watch on TV: FDSMW and FDSWI

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Cardinals -159 +134 7.5 -105 -115 -1.5 +138 -164

Cardinals vs. Brewers Prediction

Score Prediction: Brewers 5, Cardinals 4
Total Prediction: Over 7.5 runs
Win Probabilities: Cardinals 50%, Brewers 50%

Cardinals vs. Brewers Betting Insights

The Cardinals have entered the game as favorites six times this season and won twice.
St. Louis has played as favorites of -159 or more once this season and lost that game.
The implied probability of a win from the Cardinals, based on the moneyline, is 61.4%.
The Brewers have been victorious in three, or 25%, of the 12 contests they have been chosen as underdogs in this season.
Milwaukee has yet to win this season when listed as an underdog of +134 or worse on the moneyline this season.
The Brewers have an implied victory probability of 42.7% according to the moneyline set for this matchup.

Cardinals Recent Betting Performance

The Cardinals have been listed as the moneyline favorite by oddsmakers only one time in the last 10 games, and won that matchup.
In their last 10 outings — all had a set run total — the Cardinals and their opponents combined to hit the over on the total five times.
The Cardinals’ ATS record is 5-5-0 over their past 10 games.

Cardinals Recent Stats

Stat Avg/Total Record 3-7 Runs Per Game 3.8 HR 5 ERA 4.18 K/9 6.3

Cardinals Player Insights

The Cardinals best hitter thus far this season is Brendan Donovan, who’s hitting at a team-leading .356 clip along with three homers and 13 RBI.
In all of Major League Baseball, Donovan is 88th in home runs and 56th in RBI.
Donovan carries a two-game hitting streak into this matchup. In his last five games he is hitting .263 with a double, a home run, a walk and two RBI.
Lars Nootbaar’s four home runs and 14 RBI are both team-highs.
Including all MLB batters, Nootbaar ranks 49th in homers and 44th in RBI.
Nolan James Arenado has eight doubles, two home runs and 13 walks while hitting .267.
Victor Scott II is batting .275 with five doubles, a triple, a home run and eight walks.

Brewers Recent Betting Performance

In six games as underdogs over the last 10 matchups, the Brewers have a record of 2-4.
In their last 10 games with a total, the Brewers and their opponents are 4-5-1 when it comes to hitting the over.
The Brewers have six wins against the spread in their last 10 chances.

Brewers Recent Stats

Stat Avg/Total Record 5-5 Runs Per Game 5.1 HR 8 ERA 3.10 K/9 8.1

Brewers Player Insights

Turang leads the team in batting average with a high-water mark of .346.
In all of the majors, Turang ranks 88th in home runs and 44th in RBI.
Turang carries a three-game hitting streak into this matchup. During his last five outings he is batting .500 with a double, three walks and four RBI.
Jackson Chourio has hit five home runs with 20 runs batted in, leading the team in both categories.
Chourio ranks 32nd in homers and 11th in RBI among all MLB hitters this year.
Christian Yelich has been solid source of run production for the Brewers with five long balls and 20 runs batted in.
Sal Frelick is batting .312 with three doubles, two triples, a home run and 11 walks.